Daily Current Quiz for UPSC : 7 Oct 2025

Consider the following statements about the FOXP3 gene:

1. The FOXP3 gene encodes a protein that plays a critical role in the development and function of regulatory T cells, which help maintain immune tolerance.

2. Mutations in the FOXP3 gene are associated with autoimmune disorders, particularly a rare condition known as IPEX syndrome.

3. The FOXP3 gene is located on chromosome 17 and is inherited in an autosomal dominant manner.

Which of the statements given above is/are correct?

Consider the following statements about IPEX Syndrome:

1. IPEX syndrome is caused by mutations in the FOXP3 gene and primarily affects the function of cytotoxic T cells.

2. The syndrome typically presents in early infancy with severe autoimmune symptoms such as type 1 diabetes, eczema, and chronic diarrhea.

3. As an X-linked recessive disorder, IPEX predominantly affects males, with female carriers usually being asymptomatic.

Which of the statements given above is/are correct?

With reference to the 2025 Nobel Prize in Physics awarded to John Clarke, Michel Devoret, and John Martinis, consider the following statements:

1. Their award was for demonstrating macroscopic quantum mechanical tunnelling and energy quantisation in an electric circuit.

2. The experiments they performed effectively showed that quantum effects, normally confined to atomic scales, can manifest in superconducting circuits large enough to be handled macroscopic systems.

3. Their work has immediate applications in classical computing technologies, but not in quantum computing or quantum sensing.

Which of the statements given above is/are correct?

Consider the following statements about the Royal Swedish Academy of Sciences (RSAS / KVA):

1. The Academy is responsible for selecting the laureates for the Nobel Prizes in Physics, Chemistry, and Economic Sciences (i.e., the “Prize in Economic Sciences in Memory of Alfred Nobel”).

2. The Academy is a governmental body of Sweden, formally under the Ministry of Education, and its members are appointed by the Swedish Parliament.

3. The Academy also awards other international scientific prizes (apart from Nobel), promotes scientific research in Sweden, publishes scientific works, and provides scientific advice to government.

Which of the statements given above is/are correct?